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Articles from Deus Medical


DIANAMED 10 (Methandienone) for the treatment of severe cachexia resulting from AIDS

DIANAMED 10 (Methandienone) is a pharmacological drug belonging to the class of androgens and anabolic steroids (AAS). The main action of any steroid in the body is to increase the production of the male sex hormone testosterone. As a result, anabolic processes are activated, weight and physical parameters increase.

The term “cachexia” comes from the Greek words “kakos” and “hexis,” which mean “bad condition.” Cachexia is a “wasting” disorder that occurs because of the depletion of adipose tissue and muscle mass in someone who is not actively trying to lose weight. They lose weight because they eat less due to a variety of reasons. This condition affects people who are in the late stages of serious diseases like cancer, HIV or AIDS, coeliac disease, chronic obstructive pulmonary disease (COPD), kidney disease, and congestive heart failure (CHF). Other diseases also include multiple sclerosis, rheumatoid arthritis, tuberculosis, familial amyloid polyneuropathy, multiple system atrophy, mercury poisoning (acrodynia), Crohn's disease, untreated/severe type 1 diabetes mellitus, anorexia nervosa, hyperthyroidism, and hormonal deficiency.

Cachexia is associated with extreme loss of weight, muscle atrophy, fatigue, weakness and significant loss of appetite. At the same time, their metabolism changes, and this causes their body to break down too much muscle. Such factors as inflammation and substances created by tumors can affect appetite and cause the body to burn calories more quickly than usual.

Researchers state that cachexia is the body’s response to fighting disease. To get more energy necessary to fuel the brain when nutritional stores are low, the body breaks down muscle and fat. A person suffering from cachexia doesn't simply lose weight. That can be a very dangerous condition, as they get so weak and frail that their body becomes vulnerable to infections. It is a positive risk factor for death, meaning if the person has cachexia, the chance to die from their underlying condition is increased dramatically.

Cachexia physically weakens patients to a state of immobility stemming from the loss of appetite, asthenia, and anemia, at the same time the response to standard treatment is usually poor. Cachexia includes sarcopenia as a part of its pathology.

Although there is no specific treatment or way to reverse cachexia, DIANAMED 10 (Methandienone) is among effective treatments of AIDS-related cachexia. Current therapy for cachexia is aimed to achieve the main goal of treatment - to improve symptoms and quality of life. The thing is that simply getting more nutrition or calories isn’t enough to reverse cachexia.

DIANAMED 10 (Methandienone) is indicated for the treatment of severe cachexia resulting from AIDS. Also, DIANAMED 10 (Methandienone) may be utilized for treatment of cachexia of various origin, hereditary angioedema, asthenia, convalescence after serious injuries, operations, burns, in the preoperative and postoperative period, as well as after irradiation and infectious diseases, kidney and adrenal insufficiency, toxic goiter, muscular dystrophy, osteoporosis and delayed bone callus after fractures, myopathy and progressive muscular dystrophy. Additionally, DIANAMED 10 (Methandienone) is effectively used as part of complex therapy for tuberculosis, osteomyelitis, asthma, and hepatitis.