Product Partnering

Product Partnering is our major thrust area and to facilitate this process. We partner major pharmaceutical companies in India & abroad as a reliable and efficient contract manufacturer.

Articles from Deus Medical

blog

PRIMOMED 100 (Methenolone Enanthate) for the treatment of aplastic anemia

PRIMOMED 100 (Methenolone Enanthate) is a dihydrotestosterone based anabolic steroid. PRIMOMED 100 (Methenolone Enanthate) is utilized in the medical field to treat individuals suffering from conditions in which muscle wasting and severe weight loss is a symptom. PRIMOMED 100 (Methenolone Enanthate) is indicated for the treatment of aplastic anemia, breast cancer, and postmenopausal osteoporosis. Other uses also include: the drug can be used as an immunostimulant for individuals fighting infections, wasting conditions, an adjunct to countering the effects of prolonged corticosteroid therapy, and the treatment of osteoporosis as well as sarcopenia (the loss of muscle as correlated with aging).

In the case of aplastic anemia, patients suffering from this disease don’t have enough functioning red blood cells (RBCs). RBCs are the ones responsible for carrying oxygen. If the person is anemic, the body can’t transport oxygen efficiently and the person becomes tired and weak.

RBCs carry oxygen using a protein called hemoglobin, which is necessary for efficient oxygen transport. Hemoglobin tightly binds oxygen in areas with high oxygen and then releases it in areas that need oxygen. Also, it gives the red color to the blood. Hemoglobin contains iron, which is necessary for hemoglobin to bind oxygen. Mostly anemia arises from an iron deficiency. In such cases, these types of anemia are easily treatable.

That is different from aplastic anemia, which starts with a bone marrow problem and it is not caused by iron deficiency. Aplastic anemia is a very rare condition, which can be fatal if left untreated. Adult doses for the treatment of aplastic anemia are usually in a range of 1–3 mg/kg per day. Of course, like with any other steroid, adverse side effects sometimes can be present. These side effects include fluid and electrolyte retention, hypercalcemia, increased bone growth, and skeletal weight. In men patients, additional side priapism, azoospermia, hirsutism, male pattern baldness, acne, and oedema can also appear. In women patients, additional side effects include virilization, amenorrhoea, menstrual irregularities, suppressed lactation, and increased libido.

Although, PRIMOMED 100 (Methenolone Enanthate) is known to be mild in its negative side effects (it has also been utilized in children and infants to promote weight gain without any indications of ill effects or toxicity). However, in children, side effects may include premature closure of epiphyses, cessation of linear growth, and virilization symptoms.

In case of appearance of any of the following symptoms of aplastic anemia, that is advised to immediately see your doctor. In general, the symptoms of aplastic anemia are similar to general anemia. They include dizziness, excessive fatigue, sensitivity to cold temperatures, weakness, rapid heart rate, irritability, paleness, and shortness of breath. Low platelet counts can also cause nose bleeds, bleeding in the gums, the skin to bruise easily and rash with small pinpoints.