CIAMED 5 (Tadalafil)

Overview

CIAMED 5 (Tadalafil) is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate) and pulmonary arterial hypertension and improve exercise capacity in men and women. It is manufactured as 5mg tablets which contain 5mg of Tadalafil and excipients

Tadalafil mechanism of Action

Cyclic guanine monophosphate (cGMP) is needed for penile arteries and smooth muscles of the penis to relax for a man to have an erection. The amount of cGMP is reduced by an enzyme called phosphodiesterase type 5. Tadalafil inhibits this enzyme so that cyclic GMP can be more abundant leading to better and longer-lasting erection. It is this same mechanism of relaxing blood vessels and smooth muscles that also makes it useful in treating pulmonary arterial hypertension. Tadalafil has a half-life of 17.5 hours which is significantly longer than other drugs in the same category. 

Tadalafil Dosage

As prescribed by the physician.

Tadalafil Side Effects

Headache, stomach upset, back pain flushing hypertension, fatigue, UTIs, indigestion, constipation and diarrhea.

Tadalafil Interactions

Riociguat, alpha-blockers, azole antifungals, macrolides, HIV protease inhibitors, rifampin.